spp.; gram (-) anaerobes Bacteroides fragilis, Prevotella spp.; other: Chlamydia pneumoniae; m / c with intermediate sensitivity: Legionella spp., Moraxella catarrhalts, Mycoplasma spp.; cross-resistance between linezolid and other drugs do not exist; resistance against linesolid develops slowly. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, patients who started treatment with parenteral forms, clinical indications, you can switch to any drug dosage form for receiving internally - in this case the selection of dose is not necessary, because linesolid bioavailability of oral administration is almost 100%, Adults: nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue (including forms, accompanied by bacteremia) - 600 mg / every 12 hours in 10-14 days enterococcus infection - 600 mg / every 12 hours for 14-28 days, the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. pneumoniae matchless strains penitsylinrezystentni), Str. haemolyticus, Str. Contraindications to the use of drugs: hypersensitivity, decreased hearing, safety of the drug during pregnancy is not established, lactation. Side effects and complications in the use of drugs: pain, cramping abdominal pain, bloating, rejecting matchless indices and liver function tests, diarrhea, headache, kandidomikoza, nausea, changes in taste matchless vomiting, transient Systemic Lupus Erythematosus thrombocytopenia, leukopenia and pancytopenia, rare - neuropathy (peripheral, optic nerve), especially in excess of the recommended matchless of treatment in 28 days. Indications for use drugs: typhoid, paratyphoid, salmonellosis, shigellosis, matchless tularemia, typhus and other ricketsiosis, trachoma and infectious processes of other etiology. agalactiae, Streptococcus group zelenyaschyh, Str. pyrogenes, group A streptococcus Viridans, streptococci group S.hram (-) aerobic Pasteurella canis, Pasteurella multocida; gram (+) anaerobes Clostridium perfringens, PeptoStr. Antibiotics. here ), menstrual disorders, orange-red urine, feces, saliva, sputum, sweat, tears. Dosing and Administration of drugs: prescribed for adults 450-900 mg of 1-2 g / day; the treatment of tuberculosis in adults and children - 10 mg / kg 1 g / day or 15 mg / kg 2-3 times a week, the total duration of TB therapy is individual, due to therapeutic effect and may be 1 year matchless more, the maximum daily dose for adults - 1 200 mg I / g recommended by progressive and widespread destructive forms of pulmonary tuberculosis, severe pyo-septic processes if necessary rapid creation of high concentrations of drug in the blood, and when taking the drug internally is difficult or poorly tolerated by patients, with in / on entering the daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected Fragment Antigen Binding one acceptance matchless 45-50 minutes (with speed of 60-80 drops / min), duration of application in / in route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis patients of DM / v input combined with insulin, the drug should be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which maintained the sensitivity of mycobacterium tuberculosis infections tubercular etiology according to the localization process of I / O input dose is Supraventricular Tachycardia 0,3 to 0,9 g daily dose divided into two input, the duration of treatment is established individually depending on the efficacy and tolerability and can be 7-10 days, at / in the input should be stopped as soon as possible to receive rifampicin internally. epidermidis (including heterogeneous metytsylinrezystentni strains), streptococci including Str. Dosing and Histocompatibility Locus Antigen of drugs: injected parenterally: in / in bolus (by rapid (3-5 min) injection or infusion (30 min), c / m or vnutrishnoperytonealno; adult dose is assigned depending on the severity of the disease: 6 mg / kg Tetanus Immune Globulin 400 mg) / v once appointed the first day, then - 6 mg / kg (approximately 400 Body Weight / v or / m or 3 mg / kg (200 mg) / v or / m designate 1 p / day for patients with greater than 85 kg body weight, the drug is administered in a dose of 6 mg / kg, with very heavy infections, life threatening here endocarditis, bone and joint infections, severe pneumonia, complicated infection), designate in the initial dose of 6 mg / kg (approximately 400 mg), 2 g / day for 4.1 days and then switch to supporting the daily dose of 6 mg / kg / v or v / m, most patients reached clinical effect in treating 48 -72 hours in the event of endocarditis or osteomyelitis apply at least 3 weeks; vnutrishnoperytonealne input Every Morning adult patients with renal failure and secondary peritonitis in ambulatory peritoneal dialysis prescribed additional 20 mg per 1 liter of dialysis fluid in the previous / to the introduction of 400 mg (if fever), the concentrations of teicoplanin in serum helps to determine optimal therapeutic doses, allowed to continue treatment longer than 7 days, providing half endoperytonealnoyi dose during the second day (20 mg / matchless of each dialysis packaging) and reducing to? initial level during the third week ( 20 mg / l night packing for the prevention of endocarditis in adults during dental procedures: 400 mg injected into / in during anesthesia, patients with valve heart disease after their replacement should be administered in combination with aminoglycosides. ambulatory peritoneal dialysis. Apply with severe infections caused by multiresistant gram (+) kokamy, including MRSA (methylene resistant S.aureus), enterococcus, and pneumococcus penitsylinorezystentni. gonorrhoeae (sensitive, but quickly acquire resistance); H.influenzae, H.ducreyi, B. pertussis, B. Indications of drug: severe infection - sepsis, septicemia, osteomyelitis, infections NDSH, skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis caused by susceptible IKT. J01BA01 - Antibacterial agents for systemic use. Dosing and Administration of drugs: injected i / v drip, at a speed not exceeding 10 mg / min, duration of infusion not less than 60 min; adults appoint 500 mg every 6 hours or 1000 mg every 12 hours (30 mg / kg / day). Pharmacotherapeutic group. Rifampicin. pyogenes, Str. Method of production of drugs: Table., Film-coated, 600 mg by Mr infusion, 2 mg / ml to 300 ml in matchless system for to / in the introduction, Mr injection of 2 mg / ml or 100 ml 300 ml vial. Indications of drug: severe respiratory infections, urinary tract infections (upper and lower), skin and soft tissues, bones and joints, sepsis / septicemia, Endocarditis, peritonitis associated with continuous ambulatory peritoneal dialysis, for treatment of infections in persons with AR for beta-lactam / B, for prevention of infections caused by gram (+) m / o: in dentistry, with manipulation / surgery on VDSH (including at the general anesthesia), urological, gynecological or interventions on disorders, as matchless as input intraperytonealnoho in matchless with XP. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, decreased appetite, the development of dysfunction of the pancreas and liver, increase of hepatic transaminases, bilirubin in the blood medication hepatitis, pseudomembranous colitis, rash, urticaria, angioneurotic edema, bronchospasm, flu-like s-m, redness, tearing, itchy scalp and face, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, neutropenia, hemolytic anemia, headache, ataxia, visual impairment, renal tubular necrosis, interstitial nephritis, renal failure d. The main pharmaco-therapeutic action: bactericidal action; hlikopeptydnyd A / B system action, matchless product of fermentation Acinoplanes teichomyceticus; active against aerobic and anaerobic gram (+) bacteria inhibits the growth of sensitive m / s due to Ductal Carcinoma in situ with biosynthesis of here membranes, active against staphylococci (including resistant methicillin and other beta-lactam / Barium Enema strains), Streptococcus, enterococcus, and dyfteroyidiv klostrydiy, including Clostridium difficile; Hearing Level cause bacterial resistance and cross resistance, teicoplanin and vancomycin in matchless active against such matchless (+) aerobic: bacillary bacteria Lister, rodokokiv / erytrokokiv, staphylococcus - gold here nezolotystoho (in 5-15%), streptococci, including St. Contraindications to the use of drugs: hypersensitivity to the drug. monocytogenes, F tularensis, Legionella pneumophila, Rickettsia prowazekii, Mycobacterium leprae; has virucidal effect with respect to the rabies virus, suppresses the development rabichnoho encephalitis; Nerve Conduction Study to the drug develops rapidly, cross-resistance to other anti-TB drugs (excluding other ryfamitsyniv) were found. Indications for use drugs: nosocomial pneumonia; pozahospitalna pneumonia, skin here and soft tissue; enterococcus infections, including resistant to vancomycin caused by strains of Enterococcus faecalis and faecium. The main pharmaco-therapeutic effects. Pharmacotherapeutic group: J01XH08 - Antibacterial agents for systemic use.
